This Santiago hotel is located in the heart of the city. Guests that stay at the Panamericano will find that they can see a variety of attractions such as the Palace of Government, Santa Lucia Hill, and the many art galleries and museums in the area. They can also find shops, cafés, and restaurants, as well as places to experience the local nightlife. The hotel is just a short walk from the closest metro station, and the airport is only 20 km from the Panamericano. Those staying at the hotel will find public transportation that can take them to various places around the city. Some attractions are within walking distance.

The Panamericano has 145 guestrooms that include amenities such as air conditioning and heating, bathrooms, hairdryers, TV, phones, work desks, and mini bars. Guests can request a cot.

The hotel offers meeting rooms, laundry service, and meeting facilities. The Panamericano also has an onsite restaurant that serves Chilean cuisine and lounges where guests can relax.